Coatings for Ureteral Stents

Medical devices in the urinary tract can become encrusted with small crystals of mineral salts over time. These calcium and magnesium salt crystals are painful for patients and may clog the catheter or stent. Currently many urologists recommend removing and/or replacing ureteral stents within 3 months of use.

ISurTec coating will extend the lifetime of devices in the urinary tract

Uncoated

Coated

Results of accelerated encrustation assay in artificial urine at 37^oC over one month

Comparison of ISurTec-coated Ureteral Stents to Commercial Ureteral Stents

ISurTec has developed an encrustation assay in artificial urine to accelerate encrustation. The assay simulates what happens over many months in the body in a matter of weeks in the lab. Using this assay we compared calcium salt formation on several commercial ureteral stents with and without ISurTec’s anti-encrustation coating. When the calcium is dissolved from the stents and measured, ISurTec coatings reduce encrustation by >60%. Hydrophilic coatings can be applied over ISurTec’s anti-encrustation coating without reducing its ability reduce mineral salt formation.

This research is supported by the National Institute Of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health under Award Number R44DK097934. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

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ISurTec will consistently provide high quality products and services that meet requirements for medical device coatings and other scientific coatings. We will actively strive to bring excellence to the surface in all that we do, meeting or exceeding customers’ needs and expectations, and improve the quality of our products and service by enabling each employee to fulfill their job responsibilities correctly the first time.